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Specialist fields (in extracts)

Respiratory Medicine:

  • Invasive and non-invasive ventilation
  • Oxygen therapy
  • Infectious diseases
  • COPD and lung emphysema
  • Endoscopic lung volume reduction therapy, ELVR (valves, coils, thermal vapor ablation)

Sleep Medicine:

  • Sleep Apnea Syndromes (obstructive [OSA] and centra [CSA])
  • Cheyne-Stokes-Respiration (CSR)
  • Obesity-Hypoventilation-Syndrome (OHS)
  • Periodic leg movement in Disorder (PLMS, PLMD)

Curriculum vitae (in extracts)

04/1989 - 12/1995
Study in Human Medicine University of Münster, Germany
04/1996 - 03/2002
Resident, Department of Internal Medicine I Marien Hospital Herne, Ruhr University Bochum, Germany 
Specialist certification in Internal Medicine
04/2002 – 09/2007
Attending physician, Department of Internal Medicine I Marien Hospital Herne, Ruhr University Bochum, Germany
Specialist certification in sleep medicine, somnology (German Sleep Society, DGSM)
Specialist certification in Respiratory Medicine
10/2007 – 09/2014
Head of division for Respiratory and Sleep Medicine at the Marien Hospital Herne Ruhr-University Bochum, Germany
Specialization in Hypertensiology (DHL)
Specialist certification in Sleep Medicine
Venia legendi (Habilitation) for Internal Medicine at the Ruhr-University Bochum, Germany
since 10/2014
Head of Department Respiratory and Sleep Medicine Helios Hospital Duisburg Teaching Hospital HeinrichHeine-University Düsseldorf, Germany


1.Giese A, Grunwald C, Zieren J, Büchner NJ, Henning BF.

Use of the Complete Rockall Score and the Forrest Classification to Assess Outcome in 

Patients with Non-variceal Upper Gastrointestinal Bleeding Subject to After-hours 

Endoscopy: A Retrospective Cohort Study.

West Indian Med J. 2014; 63:29-33

2. Giese A, Grunwald C, Zieren J, Büchner NJ, Henning BF.

Pre-endoscopic assessment to predict outcome of acute upper gastrointestinal bleeding-

-a retrospective study in patients subject to emergency endoscopy outside regular 

working hours

Dtsch Med Wochenschr. 2013; 138:1096-101

3. Giese A, Grunwald C, Zieren J, Büchner NJ, Henning BF.

Can Pre-Endoscopic Assessment Predict Active Upper Gastrointestinal Bleeding? A 

Retrospective Study in Patients with Symptoms of Upper Gastrointestinal Bleeding 

Outside Regular Working Hours.

Hepatogastroenterology 2012, Epub ahead of print

4. Büchner NJ, Quack I, Stegbauer J, Woznowski M, Kaufmann A, Rump LC.

Treatment of obstructive sleep apnea reduces arterial stiffness

Sleep Breath. 2012 Mar;16(1):123-33.

5. Büchner NJ, Quack I, Woznowski M, Stähle C, Wenzel U, Rump LC.

Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative 

stress and improved by continuous positive airway pressure therapy

Respiration. 2011;82(5):409-17. 

6. Büchner NJ, Wissing KR, Stegbauer J, Quack I, Weiner SM, Krämer BK, Rump LC.

The renal resistance index is increased in mild-to-moderate obstructive sleep apnoea 

and is reduced under continuous positive airway pressure.

Nephrol Dial Transplant. 2011; 26:914-20 

7. Giese A, Büchner NJ, Zieren J, Henning BF.

Demands for endoscopy service outside of regular hours: a retrospective study and 

literature analysis.

Dtsch Med Wochenschr. 2010;135:2513-7

8. Vogel Y, Büchner NJ, Szpakowski M, Tannapfel A, Henning BF.

Pneumatosis cystoides intestinalis of the ascending colon related to acarbose

treatment: a case report.

J Med Case Reports. 2009 Sep 8;3:9216.

 Privatdozent Dr. med. Nikolaus Büchner

9. Woznowski M, Quack I, Stegbauer J, Büchner NJ, Rump LC, Schieren G.

Oncogenic osteomalacia, a rare paraneoplastic syndrome due to phosphate wasting--a 

case report and review of the literature. 

Clin Nephrol. 2008 Nov;70(5):431-8.

10. Vogel Y, Büchner NJ, Haverkamp T, Henning BF. 

“Familial Mediterranean fever. Rare manifestation without fever and with 

inconspicuous family case history”

Dtsch Med Wochenschr 2008; 133:1621-4. 

11. Büchner NJ, Banas B, Krämer BK. 

“Comment on: N Engl J Med. 2008 Apr 10;358(15):1547-59. Telmisartan, ramipril, or 

both in patients at high risk of vascular events.” Letter

N Engl J Med 2008; 359:426.

12. Wissing KR*, Büchner NJ*, Stegbauer J, Rump LC.

“Renal Resistance Index in Obstructive Sleep Apnea.”

Dtsch Med Wochenschr 2007; 132:1815-9, *gleichberechtigte Erstautoren, 

13. Weiner SM, Sellin L, Vonend O, Schenker P, Büchner NJ, Flecken M, Viebahn R, 

Rump LC. 

“Pneumonitis associated with sirolimus: clinical characteristics, risk factors and 

outcome--a single-centre experience and review of the literature.” 

Nephrol Dial Transplant 2007; 22:3631-7. 

14. Büchner NJ*, Sanner BM*, Borgel J, Rump LC. 

“Continuous positive airway pressure treatment of mild to moderate obstructive sleep 

apnea reduces cardiovascular risk.

Am J Respir Crit Care Med 2007; 176:1274-80. * gleichberechtigte Erstautoren

15. Bartels NK, Börgel J, Wieczorek S, Büchner NJ, Hanefeld , Bulut D, Mügge A, Rump 

LC, Sanner BM, Epplen JT. 

"Risk factors and myocardial infarction in patients with obstructive sleep apnea: impact 

of beta2-adrenergic receptor polymorphisms." 

BMC Med 2007; 5:1. 

16. Vonend O, Altenhenne C, Büchner NJ, Dekomien G, Maser-Gluth C, Weiner SM, 

Sellin L, Hofebauer S, Epplen JT, Rump LC. 

"A German family with glucocorticoid-remediable aldosteronism." 

Nephrol Dial Transplant 2007; 22:1123-30. 

17. Börgel J, Schulz T, Bartels NK, Epplen JT, Büchner NJ, Rump LC, Huesing A, 

Sanner BM, Mügge A. 

"Modifying effects of the R389G beta1-adrenoceptor polymorphism on resting heart 

rate and blood pressure in patients with obstructive sleep apnoea." 

Clin Sci (Lond) 2006; 110:117-23. 

 Privatdozent Dr. med. Nikolaus Büchner

18. Börgel J, Sanner BM, Bittlinsky A, Keskin F, Bartels NK, Büchner NJ, Huesing A, 

Rump LC, Mügge A. 

"Obstructive sleep apnoea and its therapy influence high-density lipoprotein cholesterol 

serum levels." 

Eur Respir J 2006; 27:121-7. 

19. Hägele KF, Büchner NJ, Stueckle CA, Rump LC, Weiner SM. 

"Weight loss with purpura and pain at the distal femora." 

Ann Rheum Dis 2005; 64:1373-4. 

20. Quack I, Sellin L, Büchner NJ, Theegarten D, Rump LC, Henning BF. 

"Eosinophilic gastroenteritis in a young girl--long term remission under Montelukast." 

BMC Gastroenterol 2005; 5:24. 

21. Quack I, Zwernemann C, Weiner SM, Sellin L, Henning BF, Waldherr R, Büchner NJ,

Stegbauer J, Vonend O, Rump LC. 

"Dihydrotachysterol therapy for hypoparathyroidism: consequences of inadequate 

monitoring. Five cases and a review." 

Exp Clin Endocrinol Diabetes 2005; 113:376-80. 

22. Börgel J, Sanner BM, Keskin F, Bittlinsky A, Bartels NK, Büchner NJ, Huesing A, 

Rump LC, Mügge A. 

"Obstructive sleep apnea and blood pressure. Interaction between the blood pressurelowering effects of positive airway pressure therapy and antihypertensive drugs." 

Am J Hypertens 2004; 17:1081-7. 

23. Sanner BM, Kollhosser P, Büchner NJ, Zidek W, Tepel M. 

"Influence of treatment on leptin levels in patients with obstructive sleep apnoea." 

Eur Respir J 2004; 23:601-4. 

24. Büchner NJ, Henning BF, Hägele KF, Quack IA, Rump LC. 

"Renal function in hypertensive patients with obstructive sleep apnea." 

Dtsch Med Wochenschr 2004; 129:305-9. 

25. Henning BF, Grone M, Tepel M, Büchner NJ, Kirchner J, Zidek W. 

"A rare cause of pulmonary-renal syndrome." 

Nephron 2002; 91:516-20. 

26. Büchner, NJ, Zidek W, Esser M, Haske M, Sanner BM

”Obstructive Sleep Apnea Syndrome. Effects of Therapy on Dyslipidemia.”

Somnologie 2001; 5:97-102

27. Büchner NJ.

"Acute ischemia of the legs and rapidly progressing kidney failure in a 39 year old 

woman. Contribution to N.Buchner et al. (1999) Internist 40:555-560." 

Internist (Berl) 2000; 41:87-8. 

28. Henning BF, Tepel M, Zidek W. Bertram HP, Büchner NJ.

”Lead (Pb) in fish oil capsules.”

Trace Elements and Electrolytes 2000; 3:109-111. 

 Privatdozent Dr. med. Nikolaus Büchner

29. Henning BF, Büchner NJ, Kirchner J, Gillessen A. 

"Antiphospholipid antibody syndrome as the cause of clinical rapidly progressing 


Dtsch Med Wochenschr 2000; 125:589-93. 

30. Sanner BM, Büchner NJ, Kotterba S, Zidek W. 

"Polysomnography in acute African trypanosomiasis." 

J Neurol 2000; 247:878-9. 

31. Büchner NJ., Doberauer C.

“Kompliziert verlaufende akute Hepatitis B mit multiplen extrahepatischen 


Spektrum der Hepatologie 1999; 1: 6-9

32. Büchner, N, Sanner BM, Tepel M, Doberauer C, Zidek W. 

"Acute ischemia of the legs and rapidly progressing renal failure in a 39-year-old 


Internist (Berl) 1999; 40:555-60.


  • European Respiratory Society (ERS)
  • German Respiratory Society (DGP, Deutsche Gesellschaft für Pneumologie und Beatmungsmedizin) 
  • German Sleep Society (DGSM, Deutsche Gesellschaft für Schlafforschung und Schlafmedizin) 
  • German Society for Internal Medicine (DGIM, Deutsche Gesellschaft für Innere Medizin) 
  • West German Society for Pneumology (WdGP) 
  • Nordrhein-Westfälische Gesellschaft für Schlafmedizin e.V (NRW-GSM

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